Diagnosis

VLDL Cholesterol

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Does this test have other names?

Very low-density lipoprotein cholesterol test


What is this test?

This test measures the amount of very low-density lipoprotein (VLDL) in your blood.

VLDL cholesterol is a type of blood fat. It's considered one of the "bad" forms of cholesterol, along with LDL cholesterol and triglycerides. This is because high levels of cholesterol can clog your arteries and lead to a heart attack. Sixty percent of a VLDL particle is a triglyceride.

This test is often used along with a series of other tests in a general lipid profile to screen for cardiovascular disease (CVD). High levels of VLDL cholesterol and triglycerides in your blood may mean you are at risk for CVD. People who are obese also have higher levels of VLDL cholesterol.


Why do you need this test?

You may need this test if you are at risk for CVD. Risk factors for CVD include:

  • Older age.

  • Gender–men are at higher risk.

  • Family history.

  • High blood pressure.

  • Obesity and being overweight.

  • Sedentary lifestyle.

  • Diabetes.


What other tests might you have along with this test?

You may need other tests at the same time to check your cholesterol levels, including:

  • Total cholesterol.

  • LDL (bad) cholesterol.

  • HDL (good) cholesterol.

  • Triglycerides.

You may also need other tests, such as:

  • Electrocardiogram.

  • Stress test.

  • Echocardiogram.

  • Cardiac catheterization.


What do your test results mean?

Test results may vary depending on your age, sex, health history, and other things. Your test results may be different depending on the lab used. Ask your doctor what your test results mean for you.

Results are given in milligrams per deciliter (mg/dL). Normal levels of VLDL are less than or equal to 30 mg/dL. If you have higher levels of VLDL cholesterol, you may have CVD.


How is this test done?

The test is done with a blood sample. A needle is used to draw blood from a vein in your arm or hand. 


Does this test pose any risks?

Having a blood test with a needle carries some risks. These include bleeding, infection, bruising, and feeling lightheaded. When the needle pricks your arm or hand, you may feel a slight sting or pain. Afterward, the site may be sore. 


What might affect your test results?

Eating food before your test may affect the results slightly. No other factors affect your test results.


How do you get ready for this test?

You may need to fast for 9 to 12 hours before this test. Be sure your doctor knows about all medicines, herbs, vitamins, and supplements you are taking. This includes medicines that don't need a prescription and any illegal drugs you may use.

Author: Fisher, Steve

Online Medical Reviewer: Chad Haldeman-Englert MD

Online Medical Reviewer: Raymond Turley Jr PA-C

Online Medical Reviewer: Tara Novick BSN MSN

Date Last Reviewed: 09/01/2025

© 2000-2026 The StayWell Company, LLC. All rights reserved. This information is not intended as a substitute for professional medical care. Always follow your healthcare professional's instructions.

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